Sunday, June 3, 2012

Gastro intestinal polyps

Hyperplastic polyp of stomach with intestinal metaplasia




Juvenile rectal polyp

Cribriform appearance on low power

Another of the same
More, from lower magnification






Colonic adenoma


Dysplasia is a requisite criterion

Saturday, June 2, 2012

Testis

Leydig cell tumor

Note the perivascular pattern.


Mixed germ cell neoplasm: polyembryoma

Embryonal on the left, yolk sac on the right
 The embryonal area
 And the yolk sac
 With Schiller Duval bodies

Peripheral nerves

Ganglion

A parasympathetic ganglion from around the kidney. Note the neuron cell bodies. (If you remember your anatomy lectures, parasympathetic ganglia are located in distal organs, while sympathetic ganglia form a chain right beside the spine).



Another ganglion from prostate. The cell bodies, axons with Schwann cells are clearly visible.




Blood

Pelger Heuet anomaly.







CML

Note the tapering WBC histogram

PBS

Thalassemia

A case of sickle/ thal. Note the percentage of HbF and some HbA.
PBS

Myleodysplasia

RCUD, anemia with megakaryocyte multinucleation





Sickle cells in liver




Pancreas

Histology

The dark staining exocrine pancreatic lobules surrounding an islets of langerhans. A duct is seen in right.
Islet of Langerhans

Neoplasms

Solid pseudopapillary neoplasm

A rare pancreatic tumor of young women


Cut surface is a blackish cyst
Showing normal pancreas (left) with neoplasm in right
Solid pseudopapilary neoplasm

Acute Pancreatitis
Blackened pancreas

Blackened omentum around pancreas

Fat necrosis around pancreas

Left - pancreas; right - saponified fat




Saponification

Next generation sequencing: Part 1

 Imagine solving a puzzle with 100 pieces, each piece a centimeter in size, something like this: The genome is considerably larger than this...