Tuesday, May 30, 2017

A queer blood picture

CML or CMML?

47 year old man with weakness and splenomegaly for last 7 months. Hb 9.1, WBC 1.2 L, Plt 4.7 lakhs.

Monocytes? Neutrophil precursors


Fragmented nuclei



Ring neutrophils

Florettes


Pseudo Pelger Huet cells

A similar one





Friday, May 26, 2017

Melanocytic lesions

Dermal nevus

Dermal nevus

Compound nevus

Compound nevus

Melanoma of anal canal

Anal melanoma
Dysplastic melanocytes
Dense melanin

HMB45

S100

Thursday, May 25, 2017

Tuesday, May 16, 2017

Salmonella

Salmonella typhi on Triple Sugar Iron media; glucose fermented, no carbon dioxide, H2S has turned the iron black.

Next generation sequencing: Part 1

 Imagine solving a puzzle with 100 pieces, each piece a centimeter in size, something like this: The genome is considerably larger than this...