Showing posts with label teratoma. Show all posts
Showing posts with label teratoma. Show all posts

Thursday, November 28, 2019

Teratoma

Mature cystic teratoma

An ovary (more specifically, an ovum) trying to make a (?haploid) human on its own (without a spermatocyte). And gets quite far in the process.

Bronchial epithelium, cartilage, mucosal glands (lungs)

Bronchi, cartilage, mucinous glands

Bronchial mucosa, cartilage and glands (lungs)

Mucinous columnar epithelium (? lungs)

Normal ovarian corpus luteum and stroma

Squamoid fragments (? mouth, maybe tooth)

Thyroid ('struma ovarii') , surrounding a cartilage

Neurons with synapses

Neurons

Thyroid

Thyroid with columnar epithelial lining

Eosinophilic endocrine glands (? adrenal)

Intestinal looking glands

Deep staining endocrine glands
Haploid organisms are quite common through evolution; https://www.cell.com/developmental-cell/pdf/S1534-5807(17)30345-3.pdf 

Thursday, February 2, 2012

Fresh ailments of winter 2012

A quality control slide, this one shows mucin filled columnar cells lining the bronchioles and alveoli, growing in a 'lepidic' (like butterflies on a fence) fashion over the bronchiolar epithelium. I just described bronchioloalveolar carcinoma.

 Sorry for this, hazy photograph, but the islets of small cells in an appendix speak of something ominous.

 Chromogranin

 And synaptophysin
 Carcinoid, eh? Next, an mature teratoma
 with ectodermal differentiation
 and showing mature brain tissue, complete with glia and neurones

 An omental nodule with many classical signet rings.
 On close up


This is where it comes from; a diffuse stomach neoplasm



A forehead nodule; revealed to be neural ? vascular?. Hemangiopericytoma like areas were seen. Any comments.




A newborn with a high WBC count; the cells look medium sized with cytoplasmic blebbing. Megakaryoblasts, maybe? Or transient abnormal myelopoeisis?

A bladder cancer




Next generation sequencing: Part 1

 Imagine solving a puzzle with 100 pieces, each piece a centimeter in size, something like this: The genome is considerably larger than this...