Showing posts with label histoplasma. Show all posts
Showing posts with label histoplasma. Show all posts

Saturday, May 12, 2012

MD path exam 2012

Slides from MD Path exam held at my hospital.

Atrophy? LSIL? More like the former.

The jigsaw in the dermis. A cylindroma from scalp.

The customary storage disease slide from liver

Looks like crumpled tissue

Bone marrow with lot of macrophages

which are devouring RBCs. Hemophagocytic lymphohistiocytosis.

Skin

Strain your eyes to see the pink granules in between cells. Round fungi, possibly histoplasma.
The proceedings

Hemolysis. History suggestive of microangiopathic hemolytic anemia.


Mixed cellularity Hodgkins

Neuroendocrine neoplasm. Breast

A thyroid well dermarcated thyroid lesion, with pigmented regions


Pigmented medullary carcinoma (!)

Plamsacytoid cells in PBS but with an open nucleus

Plasmablastic leukemia?

Minor salivary gland. Polymorphous low grade adenocarcinoma.

Lymph node.

Lot of macrophages.

Emperipolesis (em = inside, peri=around, polemal = wander about)

Rosai Dorfman disease

Testis FNAC

Tigroid background; large round cells with streaked out chromatin

Classical seminoma


Wednesday, August 24, 2011

The new crop: Jul - Aug 2011

Cerebral venous thrombosis

Base of skull in a case of cerebral venous thrombosis (what hath God wraught?)

Histoplasma


Some capsulated organisms in macrophages (Bone marrow of HIV +ve patient) ? Histoplasma

Castleman disease


The 'lollipop' in the lymph node

Leprosy


BT leprosy - note the nerve infiltration and well defined granulomas with giant cells



Another diffuse nerve infiltration


Neurocysticercosis

From an autopsy

Acinic cell carcinoma of parotid



Myelolipoma of adrenal gland - note the megakaryocyte






Next generation sequencing: Part 1

 Imagine solving a puzzle with 100 pieces, each piece a centimeter in size, something like this: The genome is considerably larger than this...