Showing posts with label rosai dorfman disease. Show all posts
Showing posts with label rosai dorfman disease. Show all posts

Friday, January 3, 2020

Rosai Dorfman disease

Sinus histiocytosis with massive lymphadenopathy

This disease stands out in the pantheon of weirdness: monocytes and macrophages attacking one's own lymph nodes, but not quite able to finish the job. The node remains in a stalemate.


Lymphocytes engulfed by macrophages ... 

... but not quite digested

... because they are 'self', after all

a phenomenon called 'emperipolesis'





Lymph node mostly replaced by pink macrophages

with reisdual blue lymphoid follicles








Column chromatography

 A jar of snacks (namkeens) demonstrate the principles of column chromatography to a fairly accurate extent. In a column consisting of diffe...