Sinus histiocytosis with massive lymphadenopathy
This disease stands out in the pantheon of weirdness: monocytes and macrophages attacking one's own lymph nodes, but not quite able to finish the job. The node remains in a stalemate.
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Lymphocytes engulfed by macrophages ... |
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... but not quite digested |
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... because they are 'self', after all |
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a phenomenon called 'emperipolesis' |
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Lymph node mostly replaced by pink macrophages |
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with reisdual blue lymphoid follicles |
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