Sinus histiocytosis with massive lymphadenopathy
This disease stands out in the pantheon of weirdness: monocytes and macrophages attacking one's own lymph nodes, but not quite able to finish the job. The node remains in a stalemate.
Lymphocytes engulfed by macrophages ... |
... but not quite digested |
... because they are 'self', after all |
a phenomenon called 'emperipolesis' |
Lymph node mostly replaced by pink macrophages |
with reisdual blue lymphoid follicles |
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