Sunday, December 15, 2019

Stomach

Stomach

Poorly differentiated mucinous carcinoma

Pool of mucin



Residual gastric glands




Signet ('diamond ring' cells); the nucleus is the 'diamond'







Antral type mucinous glands

More signet cells


Thursday, November 28, 2019

Teratoma

Mature cystic teratoma

An ovary (more specifically, an ovum) trying to make a (?haploid) human on its own (without a spermatocyte). And gets quite far in the process.

Bronchial epithelium, cartilage, mucosal glands (lungs)

Bronchi, cartilage, mucinous glands

Bronchial mucosa, cartilage and glands (lungs)

Mucinous columnar epithelium (? lungs)

Normal ovarian corpus luteum and stroma

Squamoid fragments (? mouth, maybe tooth)

Thyroid ('struma ovarii') , surrounding a cartilage

Neurons with synapses

Neurons

Thyroid

Thyroid with columnar epithelial lining

Eosinophilic endocrine glands (? adrenal)

Intestinal looking glands

Deep staining endocrine glands
Haploid organisms are quite common through evolution; https://www.cell.com/developmental-cell/pdf/S1534-5807(17)30345-3.pdf 

Sunday, November 17, 2019

A worm inside the appendix

Enterobius vermicularis on cross section of an appendix (9 year old child), replete with eggs.
Two worms (or a single worm in two planes) inside the lumen; note the vegetable matter inside

Inside of the worm

Characteristic Enterobius eggs

Sunday, August 4, 2019

Simulation of biological neurons

Can neurons (and neural pheonomena) be reverse engineered? Brian2 allows making customised 'neuron' objects with voltages, refractory period and synaptic delay etc. Here is a thought experiment on how far things can be stretched!
https://github.com/cmacus/biological_neuron_simulator 

Next generation sequencing: Part 1

 Imagine solving a puzzle with 100 pieces, each piece a centimeter in size, something like this: The genome is considerably larger than this...