Sunday, June 18, 2017

Adrenal gland

Normal adrenal gland. A parasympathetic ganglion is seen to the left. 


From left to right (outside inwards): Glomerulosa, fasciculata, reticularis, then some medulla, the same in reverse sequence to the right

Predominantly the fat, orange cells of fasciculata

Epidermal nevus

'Nevus' is a hamartoma of any element of skin.  So why not the epidermis itself?
Note the prominent papillomatosis, acanthosis and lamellated keratin

Acute lymphoblastic leukemia

A three year old child with weakness and bleeidng
Bone marrow
More bone marrow
Blasts
PAS

PAS; not the 'block' positivity in the center

MPO

Tuesday, May 30, 2017

A queer blood picture

CML or CMML?

47 year old man with weakness and splenomegaly for last 7 months. Hb 9.1, WBC 1.2 L, Plt 4.7 lakhs.

Monocytes? Neutrophil precursors


Fragmented nuclei



Ring neutrophils

Florettes


Pseudo Pelger Huet cells

A similar one





Friday, May 26, 2017

Melanocytic lesions

Dermal nevus

Dermal nevus

Compound nevus

Compound nevus

Melanoma of anal canal

Anal melanoma
Dysplastic melanocytes
Dense melanin

HMB45

S100

Thursday, May 25, 2017

Tuesday, May 16, 2017

Salmonella

Salmonella typhi on Triple Sugar Iron media; glucose fermented, no carbon dioxide, H2S has turned the iron black.

Next generation sequencing: Part 1

 Imagine solving a puzzle with 100 pieces, each piece a centimeter in size, something like this: The genome is considerably larger than this...