Wednesday, May 30, 2018

Keratoacanthoma

A symmetric crater in the skin filled with keratin (really low power, slide held over condenser)

With peripheral 'lipping' of keratinocytes
Usually in elderly, face-head-neck region, the crater is visible on gross. It is the smooth roundish outline of the lesion that distinguishes it from a squamous carcinoma (plus that there's no dysplasia in spite of cell enlargement towards the center)

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Next generation sequencing: Part 1

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