21M. Cystic lesion in mandible.
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| New bone formation |
Sunday, January 19, 2020
Friday, January 3, 2020
Condyloma acuminatum
Condyloma acuminatum
Anal growth, usually due to human papillomavirus infection
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| Verucous hyperplasia |
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| Koilocytes |
Squamous cell carcinoma
Poorly differentiated squamous cell carcinoma
A growth over tonsil
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| Plemorphic spindle cells |
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| Bizarre nuclei & mitotic figures |
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| Looks almost like a pleomorphic sarcoma |
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| Until you find this |
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| A keratin pearl |
Rosai Dorfman disease
Sinus histiocytosis with massive lymphadenopathy
This disease stands out in the pantheon of weirdness: monocytes and macrophages attacking one's own lymph nodes, but not quite able to finish the job. The node remains in a stalemate.
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| Lymphocytes engulfed by macrophages ... |
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| ... but not quite digested |
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| ... because they are 'self', after all |
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| a phenomenon called 'emperipolesis' |
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| Lymph node mostly replaced by pink macrophages |
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| with reisdual blue lymphoid follicles |
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Next generation sequencing: Part 1
Imagine solving a puzzle with 100 pieces, each piece a centimeter in size, something like this: The genome is considerably larger than this...
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Neutrophils (& monocytes) produce hydrogen peroxide (through superoxide production) to kill phagocytosed bacteria. 2O 2 + NADPH —> ... -
Two months in Shillong. The hilly streets. Umiam (Barapani) lake A khasi film My college principal - serendipity! ... -
56m; fever for a week; no organomegaly. Hb 2g/dL, WBC 1.18 L, Plt 40000. Peripheral blood shows 90% atypical cells: cleaved nuceli, mildly ...