Tuesday, March 29, 2011

Some breast cancers

A nice, normal TDLU.

An indian file.
More indian files, and a cancerous lobule





A lobular carcinoma growing in a 'targetoid' fashion around two ducts. The duct itself is hyperplastic/ DCIS.

Indian files again.



Intraductal papilloma/ papillary DCIS (?). Please help.

Cribriform DCIS. Note the circular punched out holes and random arrangement of round nuclei, usually orthogonal to the long axis of the duct.

Papillary DCIS? Note the fibrovascular stalks.
From the same slide as above.

Apocrine carcinoma

Mucinous carcinomaMedullary carcinoma; note the circumscription

More medullary carcinoma




And a carcinosarcoma; note the neoplastic stroma



A carcinoma growing into nerves


Cytology of a duct carcinoma

The varieties of DCIS you can get in one slide





Malignant phyllodes




Pagets disease of nipple expressing Her2



Normal estrogen receptors
Lobular carcinoma with perineural invasion






Cartilage and bone

To begin with, here is fetal cartilage made up of stellate mesenchymal cells
The initial chondroid matrix is pink, but becomes blue due to deposition of hyaluronate


This is mature, hyaline cartilage, the cells still remain stellate

And enchondral ossification (note the transition from blue to pink)
A periosteal osteosarcoma; predominantly cartilage, with a few mesenchymal cells making bone



Mesenchymal chondrosarcoma



Clouds

 On my way back from Gorakhpur